Hey,
I have issues with two of the latest games and th latest NVIDIA GeForce Drivers 350.12.
GTA 5: Crashes with Dxtory 2.0.128 after several minutes - disabling the OSD seems to be a workaround.
The same with Dxtory 2.0.129 test module.
Mortal Kombat X: Works fine with Dxtory 2.0.128 but doesn't work anymore with Dxtory 2.0.129 test module. The game won't load but closes immediately.
GTA5 isn't stable, so I think that's the cause.