I do not know why, nor what effect it would have on dxtory, but I upgraded to 32gb of ram, and now dxtory will not run, when I launch a game. Unintalled and updated to latest version, still not luck.
Windows 10 64 bit
32 gb ram
**disregard** it seems it was an issue w/ origin in game not allowing dxtory to run, it's back in working order after disabling.